Steven J Smith Selected Research

Human immunodeficiency virus 1 p31 integrase protein

1/2018	Efficacies of Cabotegravir and Bictegravir against drug-resistant HIV-1 integrase mutants.
6/2014	4-amino-1-hydroxy-2-oxo-1,8-naphthyridine-containing compounds having high potency against raltegravir-resistant integrase mutants of HIV-1.
12/2012	6,7-Dihydroxy-1-oxoisoindoline-4-sulfonamide-containing HIV-1 integrase inhibitors.
2/2012	Bicyclic hydroxy-1H-pyrrolopyridine-trione containing HIV-1 integrase inhibitors.
10/2011	Structural and functional analyses of the second-generation integrase strand transfer inhibitor dolutegravir (S/GSK1349572).

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Steven J Smith Research Topics

Disease

12	Infections 12/2021 - 03/2002
5	Acquired Immunodeficiency Syndrome (AIDS) 11/2021 - 02/2012
3	Obesity 01/2003 - 03/2002
1	Asthma (Bronchial Asthma) 01/2021
1	COVID-19 01/2021
1	Venous Thromboembolism 10/2017
1	Wounds and Injuries (Trauma) 10/2017
1	Neoplasms (Cancer) 09/2016
1	Thrombosis (Thrombus) 03/2014
1	Viremia 10/2011
1	Hemothorax 03/2010
1	Arteriovenous Malformations (Arteriovenous Malformation) 03/2010
1	Metabolic Diseases (Metabolic Disease) 04/2006
1	Spontaneous Fractures (Pathological Fracture) 08/2002
1	Hemangioma (Angioma) 08/2002
1	Compression Fractures (Compression Fracture) 08/2002
1	Perivascular Epithelioid Cell Neoplasms 06/2002
1	Insulin Resistance 04/2002
1	Muscle Cramp (Cramp) 03/2002
1	Nausea 03/2002
1	Necrosis 03/2002
1	Leiomyoma (Uterine Fibroids) 03/2002
1	Pain (Aches) 03/2002
1	Ischemia 03/2002
1	Pelvic Pain 03/2002
1	Alopecia (Baldness) 01/2002

Drug/Important Bio-Agent (IBA)

6	IntegrasesIBA 11/2021 - 02/2014
5	Human immunodeficiency virus 1 p31 integrase proteinIBA 01/2018 - 10/2011
2	NucleosidesIBA 12/2021 - 01/2016
2	Reverse Transcriptase InhibitorsIBA 12/2021 - 01/2016
2	DNA (Deoxyribonucleic Acid)IBA 09/2016 - 01/2013
2	Anti-Retroviral Agents (Antiretroviral Agents)IBA 01/2016 - 02/2014
2	EnzymesIBA 01/2016 - 01/2003
2	Raltegravir Potassium FDA Link 12/2012 - 10/2011
1	dolutegravirIBA 12/2021
1	Monoclonal AntibodiesIBA 01/2021
1	imidazole mustard (BIC)IBA 01/2020
1	Rilpivirine (TMC-278)IBA 01/2016
1	Pharmaceutical PreparationsIBA 04/2014
1	Viral DNAIBA 01/2013
1	Proteins (Proteins, Gene)FDA Link 01/2013
1	lens epithelium-derived growth factorIBA 01/2013
1	elvitegravirIBA 12/2012
1	Insulin (Novolin)FDA Link 04/2006
1	Firefly LuciferasesIBA 04/2006
1	LuciferasesIBA 04/2006
1	Triglycerides (Triacylglycerol)IBA 01/2003
1	Acyl Coenzyme A (Acyl CoA)IBA 01/2003
1	Diacylglycerol O-AcyltransferaseIBA 01/2003
1	Microphthalmia-Associated Transcription FactorIBA 06/2002
1	LeptinIBA 04/2002
1	Narcotics (Narcotic Analgesics)IBA 03/2002
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 03/2002
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 03/2002
1	LipidsIBA 01/2002

Therapy/Procedure

3	Therapeutics 01/2021 - 03/2010
1	Contraindications 10/2017
1	Thrombectomy 03/2014
1	Vertebroplasty 08/2002
1	Pain Management 03/2002
1	Conscious Sedation 03/2002
1	Therapeutic Embolization 03/2002
1	Analgesia 03/2002